Definition: Inflammation of the middle ear with the collection of fluid, without acute signs of inflammation. Also known as glue ear. Pathophysiology: The pathophysiology of glue ear is not fully known, however it is thought to be associated with Eustachian tube dysfunction. This is either thought to lead to a sterile accumulation of fluids that predisposes the middle ear to infections, or is thought to cause more acute infections of the middle ear that then leads to chronic effusion. Children with cleft palate also often have glue ear as their tensor veli palatini muscle does not attatch properly to the soft palate such that the Eustachian tube does not open on swallowing or mouth opening.